AORTA Gene: Polygenic prediction improves detection of thoracic aortic aneurysm.
James Paul PirruccelloShaan KhurshidHonghuang LinLu-Chen WangSiavash ZamirpourShinwan KanyAvanthi RaghavanSatoshi KoyamaRamachandran S VasanEmelia J BenjaminMark E LindsayPatrick T EllinorPublished in: medRxiv : the preprint server for health sciences (2023)
Genetic information improved estimation of thoracic aortic diameter when added to clinical risk factors. Larger and more diverse cohorts will be needed to develop more powerful and equitable scores.
Keyphrases
- aortic aneurysm
- risk factors
- aortic valve
- spinal cord
- genome wide
- pulmonary artery
- copy number
- aortic dissection
- loop mediated isothermal amplification
- optic nerve
- coronary artery
- label free
- health information
- real time pcr
- heart failure
- genome wide identification
- transcription factor
- gene expression
- social media
- quantum dots