Exploring the Molecular Mechanism of Astragali Radix-Curcumae Rhizoma against Gastric Intraepithelial Neoplasia by Network Pharmacology and Molecular Docking.

Yuejin JiYajun LiuJingyi HuCheng ChengJing XingLei Zhu Hong Shen

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

This study revealed the active components and molecular mechanism by which ARCR treatment is effective against GIN through regulating multipathway, such as neuroactive ligand-receptor interaction, nitrogen metabolism, and calcium signaling pathway.

Keyphrases

molecular docking
high grade
signaling pathway
molecular dynamics simulations
pi k akt
epithelial mesenchymal transition
combination therapy
oxidative stress
smoking cessation