Cognitive Trajectory Changes Over 20 Years Before Dementia Diagnosis: A Large Cohort Study.
Ge LiEric B LarsonJane B ShoferPaul K CraneLaura E GibbonsWayne McCormickJames D BowenMary Lou ThompsonPublished in: Journal of the American Geriatrics Society (2017)
Decline in average global cognitive function was evident at least 10 years before clinical diagnosis of dementia. The decline accelerated about 3 years before clinical diagnosis.