Catalytic properties and biological function of a PIWI-RE nuclease from Pseudomonas stutzeri.

Fei HuangXiaoyi XuHuarong DongNuolan LiBozitao ZhongHui LuQian LiuFan Jiang

Published in: Bioresources and bioprocessing (2022)

Our study provides the first insights into the programmable nuclease activity and biological function of the unknown PIWI-RE family of proteins, emphasizing their important role in vivo and potential application in genomic DNA modification.

Keyphrases

dna binding
cell free
single molecule
dna methylation
human health