Long-term joint outcomes in adolescents with moderate or severe haemophilia A.
David E SchmidtAikaterini MichalopoulouKathelijn FischerJayashree MotwaniNadine G AnderssonHelen PergantouSusanna Rantanull nullPublished in: Haemophilia : the official journal of the World Federation of Hemophilia (2022)
Most adolescents with severe or moderate HA show favourable joint health. Future research with combined ultrasound and/or MRI is needed to better understand joint outcomes in the remaining patients. Patents with inhibitors showed a two-fold increased proportion with joint deterioration. Ultrasound paired with physical examination increases sensitivity for detection of joint damage.
Keyphrases
- magnetic resonance imaging
- physical activity
- young adults
- end stage renal disease
- mental health
- newly diagnosed
- chronic kidney disease
- early onset
- ejection fraction
- high intensity
- risk assessment
- adipose tissue
- magnetic resonance
- prognostic factors
- peritoneal dialysis
- computed tomography
- contrast enhanced
- skeletal muscle
- current status
- sensitive detection