NMR signal enhancement of >50 000 times in fast dissolution dynamic nuclear polarization.

Luiz F PintoI Marín-MontesinosV LloverasJ L Muñoz-GómezM PonsJaume Veciana José Vidal-Gancedo

Published in: Chemical communications (Cambridge, England) (2018)

Herein, we report the synthesis and the study of a novel mixed biradical with BDPA and TEMPO radical units that are covalently bound by an ester group (BDPAesterTEMPO) as a polarizing agent for fast dissolution DNP. The biradical exhibits an extremely high DNP NMR enhancement of >50 000 times, which constitutes one of the largest signal enhancements observed so far, to the best of our knowledge.

Keyphrases

magnetic resonance
high resolution
solid state
healthcare
mass spectrometry