Intrathecal B-cell activation in LGI1 antibody encephalitis.

Klaus Lehmann-Horn Sarosh R IraniShengzhi WangArumugam PalanichamySarah JahnAriele L GreenfieldRavi DandekarGildas Lepennetier Sophia MichaelJeffrey M GelfandMichael D GeschwindMichael R WilsonScott S ZamvilH-Christian von Büdingen

Published in: Neurology(R) neuroimmunology & neuroinflammation (2020)

Our results demonstrate that intrathecal immunoglobulin repertoire expansion is a feature of LGI1 antibody encephalitis and suggests a need for CNS-penetrant therapies.

Keyphrases

machine learning
blood brain barrier
deep learning
neural network