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Thymidine Phosphorylase Promotes the Formation of Abdominal Aortic Aneurysm in Mice Fed a Western Diet.

Liang HongHong YueDunpeng CaiAutumn DeHartGretel Toloza-AlvarezLili DuXianwu ZhouXiaoping FanHuanlei HuangShiyou ChenShaik O RahamanJian ZhuangWei Li
Published in: bioRxiv : the preprint server for biology (2024)
Our findings collectively demonstrated that TYMP serves as a novel regulatory force in vascular biology, exerting influence over VSMC functionality and inflammatory responses that promote the development of AAA.
Keyphrases
  • abdominal aortic aneurysm
  • physical activity
  • high fat diet induced
  • weight loss
  • transcription factor
  • south africa
  • single molecule
  • insulin resistance