Thoracoabdominal Normothermic Regional Perfusion for Cardiac Procurement.
David L JoyceSamuel F CarlsonTakushi KohmotoLucian DurhamAdam UbertChristopher CandekDavid KoertenLyle D JoycePublished in: ASAIO journal (American Society for Artificial Internal Organs : 1992) (2022)
In donation after circulatory death donors, warm ischemia time is a significant threat to successful cardiac transplantation. The ability to perfuse these organs during the minutes after death, until cardiac evaluation is completed to satisfaction, is crucial in limiting total warm ischemic time. Thoracoabdominal normothermic regional perfusion (TANRP) has emerged as a promising strategy for recovering and monitoring these hearts. We propose a series of clinical practice pearls that we follow for all donation after circulatory death procurements to streamline the process of setting up a TANRP circuit and ensuring all team members present at time procurement are familiar with the procedure. Bicaval cannulation is achieved via the abdomen for aortic cannulation, and via the chest for right atrial cannulation, avoiding deairing maneuvers and providing the shortest possible duration from incision to initiation of cardiopulmonary bypass. Here, we describe a series of practice techniques which we have utilized in our early experience with TANRP.
Keyphrases
- extracorporeal membrane oxygenation
- left ventricular
- ultrasound guided
- clinical practice
- primary care
- quality improvement
- atrial fibrillation
- palliative care
- contrast enhanced
- aortic valve
- magnetic resonance imaging
- magnetic resonance
- pulmonary artery
- computed tomography
- stem cells
- ischemia reperfusion injury
- aortic aneurysm
- brain injury
- left atrial
- coronary artery
- blood brain barrier