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Evaluating the efficacy and safety of mavacamten in hypertrophic cardiomyopathy: A systematic review and meta-analysis focusing on qualitative assessment, biomarkers, and cardiac imaging.

Rahul VyasViraj PanchalShubhika JainManush SondhiMansunderbir SinghKeerthish JaisinghSahith Reddy ThotamgariAnuj ThakreKalgi Modi
Published in: PloS one (2024)
Mavacamten influences diverse facets of HCM comprehensively. Notably, our study delved into the drug's impact on the heart's structural and functional aspects, providing insights that complement prior findings. Further large-scale trials are needed to evaluate the safety profile of Mavacamten.
Keyphrases
  • hypertrophic cardiomyopathy
  • left ventricular
  • heart failure
  • high resolution
  • systematic review
  • mass spectrometry
  • drug induced