Lymphocyte profile and cytokine mRNA expression in peripheral blood mononuclear cells of patients with recurrent respiratory papillomatosis suggest dysregulated cytokine mRNA response and impaired cytotoxic capacity.

Anna HolmOlga NagaevaIvan NagaevChristos LoizouGöran LaurellLucia Mincheva-NilssonKarin NylanderKatarina Olofsson

Published in: Immunity, inflammation and disease (2017)

These findings demonstrate an immune dysregulation with inverted CD4+ /CD8+ ratio and aberrant cytokine mRNA production in RRP patients, compared to healthy controls.

Keyphrases

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prognostic factors
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