Exploring antiviral effect and mechanism of Jinye Baidu granules(JYBD)against influenza A virus through network pharmacology and in vitro and invivo experiments.
Zhixuan ChenQinxian MoSiqi LuoJinlong LiangYinyan LiYinhuang GaoChunyu ZhangLinrui JiangJun MaSizu YangFeng JiangMenghua LiuShuwen LiuJie YangPublished in: Journal of ethnopharmacology (2024)
JYBD could inhibit IAV replication and mitigate virus-induced excessive inflammatory response. Combinations of JYBD and neuraminidase inhibitors conferred synergistic suppression of IAV both in vitro and in vivo. It might provide a scientific basis for clinical applications of JYBD against influenza virus infected diseases.