Login / Signup

Exploring antiviral effect and mechanism of Jinye Baidu granules(JYBD)against influenza A virus through network pharmacology and in vitro and invivo experiments.

Zhixuan ChenQinxian MoSiqi LuoJinlong LiangYinyan LiYinhuang GaoChunyu ZhangLinrui JiangJun MaSizu YangFeng JiangMenghua LiuShuwen LiuJie Yang
Published in: Journal of ethnopharmacology (2024)
JYBD could inhibit IAV replication and mitigate virus-induced excessive inflammatory response. Combinations of JYBD and neuraminidase inhibitors conferred synergistic suppression of IAV both in vitro and in vivo. It might provide a scientific basis for clinical applications of JYBD against influenza virus infected diseases.
Keyphrases
  • inflammatory response
  • high glucose
  • diabetic rats
  • lipopolysaccharide induced
  • weight gain
  • toll like receptor
  • cancer therapy
  • oxidative stress
  • physical activity
  • drug delivery
  • immune response
  • network analysis