2,3,5,4'-Tetrahydroxystilbene (TG1), a Novel Compound Derived from 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside (THSG), Inhibits Colorectal Cancer Progression by Inducing Ferroptosis, Apoptosis, and Autophagy.
Kuei-Yen TsaiPo-Li WeiCheng-Chin LeePrecious Takondwa MakondiHsin-An ChenYao-Yuan ChangDer-Zen LiuChien-Yu HuangYu-Jia ChangPublished in: Biomedicines (2023)
These findings suggest that TG1 might be a potential and potent compound for clinical use in the treatment of CRC by inhibiting proliferation and inducing ferroptosis through the MYC pathway.