Effect of Glucose Levels on Cardiovascular Risk.
Anastasia V PoznyakLarisa S LitvinovaPoggio PaoloVasily Nikolaevich SukhorukovAlexander N OrekhovPublished in: Cells (2022)
Cardiovascular diseases remain the leading cause of death and disability. The development of cardiovascular diseases is traditionally associated with various risk factors, most of which are somehow related to an unhealthy lifestyle (smoking, obesity, lack of physical activity, etc.). There are also risk factors associated with genetic predisposition, as well as the presence of concomitant diseases, especially chronic ones. One of the most striking examples is, of course, type 2 diabetes. This metabolic disorder is associated with impaired carbohydrate metabolism. The main clinical manifestation of type 2 diabetes is elevated blood glucose levels. The link between diabetes and CVD is well known, so it is logical to assume that elevated glucose levels may be important, to some extent, in the context of heart and vascular disease. In this review, we tried to summarize data on the possible role of blood glucose as a risk factor for the development of CVD.
Keyphrases
- blood glucose
- glycemic control
- type diabetes
- cardiovascular disease
- weight loss
- physical activity
- risk factors
- insulin resistance
- metabolic syndrome
- blood pressure
- multiple sclerosis
- cardiovascular risk factors
- body mass index
- electronic health record
- smoking cessation
- atrial fibrillation
- weight gain
- depressive symptoms
- gene expression
- artificial intelligence
- copy number
- data analysis