Rehmapicrogenin attenuates lipopolysaccharide-induced podocyte injury and kidney dysfunctions by regulating nuclear factor E2-related factor 2/antioxidant response element signalling.

Xiaohong MaGuandong LiYufeng ShiZhitao Shang

Published in: Nephrology (Carlton, Vic.) (2024)

Rehmapicrogenin relieves the podocyte injury and renal dysfunctions through activating the Nrf2/ARE pathway to inhibit apoptosis and oxidative stress.

Keyphrases

oxidative stress
lipopolysaccharide induced
nuclear factor
inflammatory response
toll like receptor
diabetic nephropathy
dna damage
diabetic rats
ischemia reperfusion injury
induced apoptosis
high glucose
signaling pathway
heat shock
cell death
endothelial cells
cell proliferation
pi k akt