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Hypofibrinolysis in pediatric patients with veno-occlusive disease in hematopoietic stem cell transplantation.

Veronika KlausKarin Melanie Cabanillas StanchiKarina AlthausSarah SchoberSebastian MichaelisChristian SeitzPeter LangRupert HandgretingerTamam BakchoulStefanie HammerMichaela Döring
Published in: Journal of cancer research and clinical oncology (2023)
These results suggest that HSCT patients exhibit reduced fibrinolytic capacities and patients diagnosed with VOD show signs of hypofibrinolysis. This prospective study shows that fibrinolysis can be assessed in a rapid and accessible way via thrombelastography. Thrombelastography might be a parameter to support the diagnosis of a VOD and to serve as a follow-up parameter after the diagnosis of a VOD.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • peritoneal dialysis
  • prognostic factors
  • extracorporeal membrane oxygenation
  • patient reported
  • sickle cell disease