Cytological differences between invasive and noninvasive or minimally invasive lung adenocarcinomas diagnosed in Japanese patients using needle biopsy specimens of pulmonary lesions ≤3 cm in diameter.
Jun MatsubayashiShinji MiyakeYujin KudoYoshihisa ShimadaJunichi MaedaHisashi SajiMasatoshi KakihanaJinho ParkNaohiro KajiwaraShigeru InoueKazuhiro SaitoTatsuo OhiraNorihiko IkedaKoichi TokuuyeToshitaka NagaoPublished in: Diagnostic cytopathology (2019)
Large or 3D tumor cell clusters and irregular nuclear contours may be important cytological factors for distinguishing IAD from NMIAD, with the latter being potentially more important for distinguishing between the two groups.