Pooled analysis on image-guided moderately hypofractionated thoracic irradiation in inoperable node-positive/recurrent patients with non-small cell lung cancer with poor prognostic factors and severely limited pulmonary function and reserve.
Chukwuka EzeJulian Elias GuggenbergerNina-Sophie Schmidt-HegemannSaskia KenndoffJulian TaugnerLukas KäsmannStephan SchöneckerBenedikt FlörschMinglun LiClaus BelkaFarkhad ManapovPublished in: Cancer (2022)
Patients with inoperable node-positive NSCLC, a poor performance status, and severely limited lung function can be safely and effectively treated with individualized moderately hypofractionated IGRT. The achieved survival rates for this highly multimorbid group of patients were encouraging.
Keyphrases
- prognostic factors
- lung function
- radiation therapy
- end stage renal disease
- newly diagnosed
- cystic fibrosis
- small cell lung cancer
- chronic obstructive pulmonary disease
- ejection fraction
- air pollution
- chronic kidney disease
- brain metastases
- spinal cord
- peritoneal dialysis
- squamous cell carcinoma
- radiation induced
- free survival
- epidermal growth factor receptor