Disease control of acromegaly does not prevent excess mortality in the long term: results of a nationwide survey in Italy.
M ArosioV SciannameoContarino AndreaP BerchiallaS PuglisiA C PesatoriE FerranteM FilopantiR PivonelloF DassieV RochiraS CannavòE De MenisF PigliaruS GrottoliV CambriaM Faustini-FustiniM MontiniA PeriF CeccatoE PuxedduG BorrettaM BondanelliD FeroneA ColaoM TerzoloG ReimondoPublished in: Journal of endocrinological investigation (2024)
Mortality remains significantly high in patients with acromegaly, irrespectively of disease status, as long as the follow-up is sufficiently long with a low rate of patients lost to follow-up. Therapy strategy including radiotherapy does not have an impact on mortality. Oncological causes of death currently outweigh the cardiovascular causes.
Keyphrases
- cardiovascular events
- end stage renal disease
- risk factors
- newly diagnosed
- ejection fraction
- chronic kidney disease
- early stage
- prostate cancer
- prognostic factors
- peritoneal dialysis
- rectal cancer
- coronary artery disease
- type diabetes
- squamous cell carcinoma
- locally advanced
- stem cells
- radiation induced
- growth hormone
- robot assisted