Association of Testosterone and Sex Hormone-Binding Globulin With All-Cause and Cardiovascular Disease Mortality in Older Chinese Men.
Mei Jiao LiChao Qiang JiangYa Li JinTong ZhuFeng ZhuWei Sen ZhangLin XuPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2024)
Higher total testosterone, free testosterone, and bioavailable testosterone were associated with higher all-cause mortality in older men, higher free testosterone was associated with higher CVD mortality whilst lower SHBG was associated with higher all-cause and CVD mortality. Clarification and confirmation of causality require further mechanistic studies.