Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation.
Funsho E FakuadeDominik HubrichtVanessa MöllerIzzatullo SobitovAiste LiutkuteYannic DöringFitzwilliam SeibertzMarcus GerloffJulius Ryan D ProntoFereshteh HaghighiSören BrandenburgKhaled AlhussiniNadezda IgnatyevaYara BonhoffStefanie KestelAschraf El-EssawiAhmad Fawad JebranMarius GroßmannBernhard C DannerHassina BarakiConstanze SchmidtSamuel SossallaIngo KutschkaConstanze BeningChristoph MaackWolfgang A LinkeJordi HeijmanStephan E LehnartGeorge KensahAntje EbertFleur E MasonNiels VoigtPublished in: Circulation (2024)
release events and atrial fibrillation susceptibility. Strategies targeting intracellular buffering may represent a promising therapeutic lead in persAF management.