Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy.
Catalina BarcelóMonia GuidiChristian W ThorballChristian HammerAziz ChaouchAlexandra U ScherrerBarbara HasseMatthias CavassiniHansjakob FurrerAlexandra CalmySebastian HaubitzEnos BernasconiThierry BuclinJacques FellayPhilip E TarrChantal Csajkanull nullPublished in: Open forum infectious diseases (2020)
The risk of general and abdominal obesity increased with CD4 nadir <100 cells/µL. Based on our results, including the genetic background would not improve obesity predictions in HIV-infected individuals.
Keyphrases
- hiv infected
- antiretroviral therapy
- insulin resistance
- human immunodeficiency virus
- weight loss
- metabolic syndrome
- hiv positive
- hiv infected patients
- hiv aids
- high fat diet induced
- type diabetes
- induced apoptosis
- weight gain
- genome wide
- body mass index
- copy number
- cell cycle arrest
- adipose tissue
- endoplasmic reticulum stress
- signaling pathway
- cell proliferation
- cell death
- body weight
- hepatitis c virus
- nk cells