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Analysis of Sequence Variation and Risk Association of Human Papillomavirus 52 Variants Circulating in Korea.

Youn Jin ChoiEun Young KiChuqing ZhangWendy C S HoSung-Jong LeeMin Jin JeongPaul K S ChanJong Sup Park
Published in: PloS one (2016)
To our knowledge, we are the first to reveal the predominance of the HPV52 lineages, B and C, in Korea. We also found these lineages harbored distinct genetic alterations that may affect oncogenicity. Our findings increase our understanding on the heterogeneity of HPV52 variants, and may be useful for the development of new diagnostic assays and therapeutic vaccines.
Keyphrases
  • copy number
  • genome wide
  • high grade
  • single cell
  • healthcare
  • cervical cancer screening
  • dna methylation