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CSF evidence of pericyte damage in Alzheimer's disease is associated with markers of blood-brain barrier dysfunction and disease pathology.

James S MinersP G KehoeS LoveH ZetterbergK Blennow
Published in: Alzheimer's research & therapy (2019)
We provide further evidence of an association between pericyte injury and BBB breakdown in AD and novel evidence that a CSF marker of pericyte injury is related to the severity of AD pathology.
Keyphrases
  • blood brain barrier
  • cerebral ischemia
  • oxidative stress
  • cerebrospinal fluid
  • brain injury