Field template-based design and biological evaluation of new sphingosine kinase 1 inhibitors.

Heba AlshakerShyam SrivatsDanielle MonteilQi WangCaroline M R LowDmitri Pchejetski

Published in: Breast cancer research and treatment (2018)

Through field template screening, we have identified a new SK1 inhibitor, SK-F, which demonstrated antitumour activity in vitro and in vivo without overt toxicity when combined with DTX.

Keyphrases

molecularly imprinted
oxidative stress