Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis.
Saber D BarbarRaphaël Clere-JehlAbderrahmane BourredjemRomain HernuFlorent MontiniRémi BruyèreChristine LebertJulien BohéJulio BadieJean-Pierre EraldiJean-Philippe RigaudBruno LevyShidasp SiamiGuillaume LouisLila BouadmaJean-Michel ConstantinEmmanuelle MercierKada KloucheDamien du CheyronGaël PitonDjillali AnnaneSamir JaberThierry van der LindenGilles BlascoJean-Paul MiraCarole SchwebelLoïc ChimotPhilippe GuiotMai-Anh NayFerhat MezianiJulie HelmsClaire RogerBenjamin LouartRemi TrussonAuguste DargentChristine BinquetJean-Pierre Quenotnull nullPublished in: The New England journal of medicine (2018)
Among patients with septic shock who had severe acute kidney injury, there was no significant difference in overall mortality at 90 days between patients who were assigned to an early strategy for the initiation of renal-replacement therapy and those who were assigned to a delayed strategy. (Funded by the French Ministry of Health; IDEAL-ICU ClinicalTrials.gov number, NCT01682590 .).