Syringin from Tinospora crispa downregulates pro-inflammatory mediator production through MyD88-dependent pathways in lipopolysaccharide (LPS)-induced U937 macrophages.

Laiba ArshadMd Areeful HaqueHemavathy HarikrishnanSarah IbrahimIbrahim Jantan

Published in: Molecular biology reports (2024)

The suppressive effect of syringin on the inflammatory signaling molecules in MyD88-dependent pathways suggested it's potential as a drug candidate for development into an agent for treatment of various immune-mediated inflammatory disorders.

Keyphrases

lps induced
inflammatory response
toll like receptor
oxidative stress
immune response
emergency department
combination therapy
human health
adverse drug
smoking cessation
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