AHRR cg05575921 methylation in relation to smoking and PM2.5 exposure among Taiwanese men and women.

Disline Manli TantohMing-Chi WuChun-Chao ChuangPei-Hsin ChenYeu Sheng TyanOswald Ndi NforWen-Yu LuYung Po Liaw

Published in: Clinical epigenetics (2020)

Smoking and PM2.5 were independently associated with hypomethylation of cg05575921, cg23576855, cg03636183, and cg21911711. The most hypomethylated CpG site was cg05575921 and its association with smoking and PM2.5 was dose-dependent.

Keyphrases

particulate matter
air pollution
smoking cessation
heavy metals
polycyclic aromatic hydrocarbons
dna methylation
water soluble
gene expression
risk assessment