Neurocognition in Congenital Central Hypoventilation Syndrome: influence of genotype and ventilation method.
Ha TrangPauline BourgeoisFawzia Cheliout-HerautPublished in: Orphanet journal of rare diseases (2020)
CCHS increased the risk to develop neurocognitive deficiencies, affecting particularly speed of processing and working memory. Our results suggested that both genetics and ventilation method could be also involved in the physiopathology of neurocognitive impairment. Further investigations were required to untangle the complex underlying processes. Neurocognitive assessments should be performed regularly in children with CCHS in order to plan re-education programs, adapt school integration and improve quality of life.
Keyphrases
- working memory
- bipolar disorder
- transcranial direct current stimulation
- respiratory failure
- healthcare
- physical activity
- attention deficit hyperactivity disorder
- mechanical ventilation
- young adults
- mental health
- public health
- quality improvement
- obstructive sleep apnea
- intensive care unit
- extracorporeal membrane oxygenation