Identification of Desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells.

Sabine BerneggerRobert VidmarMarko FonovicGernot PosseltBoris TurkSilja Wessler

Published in: Cell communication and signaling : CCS (2021)

Characterizing the substrate specificity of HpHtrA revealed efficient hDsg2 cleavage underlining the importance of HpHtrA in opening intercellular junctions. Video Abstract.

Keyphrases

helicobacter pylori
structural basis
helicobacter pylori infection
single molecule
single cell
dna binding
bioinformatics analysis
cell adhesion
amino acid