Combined application of neural stem/progenitor cells and scaffolds on locomotion recovery following spinal cord injury in rodents: a systematic review and meta-analysis.
Mahmoud YousefifardShaghayegh Askarian-AmiriSolmaz Nasseri MalekiSeyedeh Niloufar Rafiei AlaviArian Madani NeishabooriLeila HaghaniAlexander R VaccaroJames S HarropYi LuVafa Rahimi-MovagharMostafa HosseiniPublished in: Neurosurgical review (2022)
The findings showed that using NS/PCs with scaffold not only improves locomotion recovery, but also is superior to NS/PCs alone and scaffold alone. Future experiments and translational clinical studies are recommended to focus on the assessment of the safety and efficacy of the application of NS/PC + scaffold on SCI recovery.