NAA is a Marker of Disability in Secondary-Progressive MS: A Proton MR Spectroscopic Imaging Study.
Bhavana S SolankyNevin A JohnFloriana De AngelisJonathan StuttersFerran Prados CarrascoTorben SchneiderRichard Anthony ParkerChristopher J WeirAnita MonteverdiDomenico PlantoneA DoshiDavid MacManusIan MarshallFrederik BarkhofClaudia A M Gandini Wheeler-KingshottJeremy Chatawaynull nullPublished in: AJNR. American journal of neuroradiology (2020)
This study suggests that metabolic markers of neuroaxonal integrity and astrogliosis in normal-appearing WM and membrane turnover in GM may act as markers of disability in secondary-progressive MS.