Prognostic analysis of CD5 expression in double-hit diffuse large B-cell lymphoma and effectiveness comparison in patients treated with dose-adjusted EPOCH plus rituximab/R-CHOP regimens.
Fangwen ZhangLing LiLei ZhangXin LiXiaorui FuXinhua WangJingjing WuZhenchang SunFei KongLiangliang RenMingzhi ZhangPublished in: Blood and lymphatic cancer : targets and therapy (2019)
Our retrospective study shows that CD5+ has a poorer prognosis than CD5- patients. Based on its improved lifetime and good tolerance on CD5+ patients, which is expected to become the first-line treatment for high-risk DLBCL types based on more clinical research.