Simple systemic index associated with oxaliplatin-induced liver damage can be a novel biomarker to predict prognosis after resection of colorectal liver metastasis.

Tomonari ShimagakiKeishi SugimachiYohei ManoEmi OnishiTomohiro IguchiHideo UeharaMasahiko SugiyamaManabu YamamotoMasaru MoritaYasushi Toh

Published in: Annals of gastroenterological surgery (2022)

The APRI and TBS in patients with CRLM are prognostic predictors after hepatectomy for metastatic liver cancer. This study indicated that liver damage in patients treated with preoperative oxaliplatin has an effect on the prognosis.

Keyphrases

oxidative stress
squamous cell carcinoma
small cell lung cancer
diabetic rats
high glucose
patients undergoing
endothelial cells