Renoprotective effects of dexmedetomidine against ischemia-reperfusion injury in streptozotocin-induced diabetic rats.

Seung Hyun KimJi Hae JunJu Eun OhEun-Jung ShinYoung Jun OhYong Seon Choi

Published in: PloS one (2018)

This study shows that the protective effects of DEX in renal ischemia-reperfusion injury are preserved in diabetic conditions and may potentially provide a basis for the use of DEX in clinical treatment of renal ischemia-reperfusion injury.

Keyphrases

diabetic rats
oxidative stress
ischemia reperfusion injury
type diabetes
cardiac surgery
diabetic nephropathy
combination therapy
high fat diet
smoking cessation