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Synthesis, properties and chemical modification of a persistent triisopropylsilylethynyl substituted tri(9-anthryl)methyl radical.

Tomohiko NishiuchiDaisuke IshiiSeito AibaraHiroyasu SatoTakashi Kubo
Published in: Chemical communications (Cambridge, England) (2022)
In studies aimed at developing new organic spin materials, we prepared a triisopropylsilylethynyl substituted tri(9-anthryl)methyl (TAntM) radical. The TIPS-ethynyl group in this radical effectively suppresses its reactivity, resulting in extremely high stability in air for at least one month. Chemical modification of the radical using [4+2] Diels-Alder reaction proceeds even at room temperature. Because harsh conditions and metal-catalyzed reactions are not required, this post-modification strategy should be highly versatile for use in constructing unique spin-labelled molecules.
Keyphrases
  • room temperature
  • ionic liquid
  • molecular docking
  • signaling pathway
  • density functional theory
  • single molecule
  • molecular dynamics