ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells.

Li-Kuang TsaiMin PengChia-Chun ChangLuan WenLin LiuXiubin LiangY Eugene ChenJie XuLi-Ying Sung

Published in: Cell & bioscience (2023)

These data reveal that PARP1 and ZSCAN4 have a protein-protein interaction, and shed light on the molecular mechanisms by which ZSCAN4 reduces DSB in mESCs.

Keyphrases

dna repair
protein protein
embryonic stem cells
dna damage
small molecule
dna damage response
electronic health record
genome wide
big data
oxidative stress
binding protein
single cell
dna methylation
gene expression
data analysis