Neointimal hyperplasia in systemic-to-pulmonary shunts of children with complex cyanotic congenital heart disease.
Philip KottmannJulie CleuziouJulia LemmerKatja EildermannKeti VitanovaMaria Von StummLuisa LehmannJürgen HörerPeter EwertMatthias SiglerCordula M WolfPublished in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2022)
In infants with complex cyanotic congenital heart disease, neointimal hyperplasia in systemic-to-pulmonary shunts is associated with early interventions comprising balloon dilatation, stent implantation and shunt revision. Smaller shunt size and lower aspirin dosage are associated with increased neointimal proliferation.
Keyphrases
- congenital heart disease
- smooth muscle
- vascular smooth muscle cells
- pulmonary hypertension
- pulmonary artery
- low dose
- total knee arthroplasty
- young adults
- physical activity
- cardiovascular events
- antiplatelet therapy
- pulmonary arterial hypertension
- total hip arthroplasty
- acute coronary syndrome
- coronary artery disease
- percutaneous coronary intervention
- anti inflammatory drugs