Impacts of PAH accumulation on reproductive hormones, indices of oxidative stress and BPDE-albumin adduct in women with recurrent pregnancy loss.
Amany El-SikailyMohamed HelalAugusta Chinyere Nsonwu-AnyanwuHossam AzabNeveen Abd ElMoneimEman Othman Salem FarahatAziza SaadPublished in: Toxicological research (2023)
High PAH exposure in pregnant women is associated with 10-epoxide-albumin adduct formation and high MDA levels in their sera. On the other hand, PAH exposure in those women led to a decrease in their GSH, catalase, P4, and FSH sera levels. These findings indicate that PAH exposure can exert different physiological effects in pregnant women leading to a high level of abortion in those women.