Sulindac, a Nonselective NSAID, Reduces Breast Density in Postmenopausal Women with Breast Cancer Treated with Aromatase Inhibitors.
Patricia A ThompsonChuan HuangJie YangBetsy C WertheimDenise RoeXiaoyue ZhangJie DingPavani ChalasaniChristina PreeceJessica MartinezH-H Sherry ChowAlison T StopeckPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
This is the first study to indicate that the NSAID sulindac may reduce BD. Additional studies are needed to verify these findings and determine if prostaglandin E2 inhibition by NSAIDs is important for BD or collagen modulation.