MRI targeted single fraction HDR Brachytherapy for localized Prostate Carcinoma: a feasibility study of focal radiation therapy (ProFocAL).
Frank FischbachPeter HassDaniel SchindelePhilipp GensekeLisa GeisendorfChristian StehningMartin SchostakThomas BrunnerMaciej PechKatharina FischbachPublished in: European radiology (2019)
• MR-guided focal HDR brachytherapy allows an accurate placement of catheters with maximum therapeutic dose distribution restricted to the tumor. • No major anesthesia or antibiosis is necessary emphasizing the minimal invasive character of the procedure. • Patients with low- and intermediate-risk prostate carcinoma in particular may benefit to halt disease progression whereas treatment-related morbidity is reduced compared with radical therapy.
Keyphrases
- radiation therapy
- prostate cancer
- high dose
- contrast enhanced
- benign prostatic hyperplasia
- locally advanced
- magnetic resonance imaging
- radiation induced
- magnetic resonance
- high resolution
- computed tomography
- low dose
- stem cells
- diffusion weighted imaging
- squamous cell carcinoma
- ultrasound guided
- bone marrow
- mass spectrometry
- drug induced