RPTOR methylation in the peripheral blood and breast cancer in the Chinese population.

Yifei YinShuifang LeiLixi LiXiaoqin YangQiming YinTian XuWenjie ZhouHong LiWanjian GuFei MaRongxi YangZhengdong Zhang

Published in: Genes & genomics (2021)

Our study validated the association between hypomethylation of RPTOR and BC risk in the Chinese population also with weak effect and mostly for postmenopausal women. In addition, our findings provided novel insight for the regulation of DNA methylation upon aging or the change of hormone levels.

Keyphrases

postmenopausal women
dna methylation
peripheral blood
bone mineral density
genome wide
gene expression
body composition
copy number