GWAS in people of Middle Eastern descent reveals a locus protective of kidney function-a cross-sectional study.

Siham A Mohamed Juan Fernadez-Tajes Paul W Franks Louise Bennet

Published in: BMC medicine (2022)

The genetic effects discovered here may help explain why people from the Middle East have better kidney function than those of European descent. Genetic predisposition to preserved kidney function may also underlie the observed survival benefits in Middle Eastern immigrants with type 2 diabetes.

Keyphrases

south africa
genome wide
copy number
physical activity
risk factors
genome wide association study
dna methylation
gene expression
free survival