Regional distribution of mechanical strain and macrophage-associated lung inflammation after ventilator-induced lung injury: an experimental study.
Francesco LiggieriElena ChiodaroliMariangela PellegriniEmmi PuuvuoriJonathan SigfridssonIrina VelikyanDavide ChiumelloLorenzo BallPaolo PelosiSebastiano StramagliaGunnar AntoniOlof ErikssonGaetano PerchiazziPublished in: Intensive care medicine experimental (2024)
Ga]Ga-DOTA-TATE uptake at voxel level, suggesting that mechanical alteration and specific activation of inflammatory cells are strongly linked in VILI. This study represents the first voxel-by-voxel examination of this relationship in a multi-modal imaging analysis.