Immune Checkpoint Therapy Combinations in Adult Advanced MiT Family Translocation Renal Cell Carcinomas.
Omar AlhalabiJonathan ThouveninSylvie NégrierYann-Alexandre VanoLuca CampedelElshad HasanovZiad BakounyAndrew W HahnMehmet Asim BilenPavlos MsaouelToni K ChoueiriSrinivas R ViswanathanKanishka SircarLaurence AlbigesGabriel G MaloufNizar M TannirPublished in: The oncologist (2023)
In this retrospective study of advanced tRCC, limited response and survival were seen after frontline dual ICT combination therapy, while ICT + VEGF TT therapy offered some efficacy. Due to the heterogeneity of tRCC, insights into the biological underpinnings are necessary to develop more effective therapies.