LINC01119 negatively regulates osteogenic differentiation of mesenchymal stem cells via the Wnt pathway by targeting FZD4.

Hongwei GaoHui DongJiachun ZhengXufeng JiangMingzhi GongLe HuJinshan HeYong-Xiang Wang

Published in: Stem cell research & therapy (2022)

We first explored the molecular regulatory mechanism of LINC01119 during the osteogenic differentiation of MSCs and revealed that LINC01119 negatively regulates osteogenesis through the Wnt pathway by targeting FZD4.

Keyphrases

cell proliferation
mesenchymal stem cells
long non coding rna
long noncoding rna
umbilical cord
stem cells
bone marrow
single cell
single molecule