The rapid Bethesda assay is equivalent to the standard Bethesda assay for detection of factor IX inhibitors in patients with severe haemophilia B.
Mervyn SahudOlga ZhukovStanley J NaidesCynthia SerranoEdward C C WongJeffrey DlottFrederick RackePublished in: Haemophilia : the official journal of the World Federation of Hemophilia (2020)
The rapid Bethesda assay showed good agreement with the standard Bethesda assay for determination of inhibitor levels in patients with severe haemophilia B. The rapid assay allows for faster assessment of inhibitors in patients with severe haemophilia B and has the potential to improve the ability of the coagulation laboratory to perform testing from a logistical viewpoint. Further studies involving larger numbers of patients would be important to confirm our findings.