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Vaginal microbial dynamics and pathogen colonization in a humanized microbiota mouse model.

Marlyd E MejiaVicki Mercado-EvansJacob J ZulkSamantha OttingerKorinna RuizMallory B BallardRobert A BrittonKathryn A Patras
Published in: bioRxiv : the preprint server for biology (2023)
assays. We propose that this humanized microbiota mouse platform is an improved model to describe the role of the vaginal microbiota in protection against urogenital pathogens. Furthermore, this model will be useful in testing efficacy of new probiotic strategies in the complex vaginal environment.
Keyphrases
  • mouse model
  • high throughput
  • monoclonal antibody
  • microbial community
  • candida albicans
  • multidrug resistant