Login / Signup

Heterozygous mutations of HTRA1 gene in patients with familial cerebral small vessel disease.

Ilaria Di DonatoSilvia BianchiGian Nicola GallusAlfonso CeraseIlaria TagliaFrancesca PesciniSerena NannucciCarla BattistiDomenico InzitariLeonardo PantoniAndrea ZiniAntonio FedericoMaria Teresa Dotti
Published in: CNS neuroscience & therapeutics (2017)
Our observation further supports the pathogenic role of the heterozygous HTRA1 mutations in familial SVD.
Keyphrases
  • early onset
  • subarachnoid hemorrhage
  • genome wide
  • cerebral ischemia
  • transcription factor
  • blood brain barrier
  • cerebral blood flow