Drug-induced shortening of the electromechanical window is an effective biomarker for in silico prediction of clinical risk of arrhythmias.

Elisa PassiniCristian TrovatoPierre MorissetteFrederick SannajustAlfonso Bueno-OrovioBlanca Rodriguez

Published in: British journal of pharmacology (2019)

The EMw is an effective biomarker for in silico predictions of drug-induced clinical pro-arrhythmic risk, particularly for compounds with multichannel blocking action.

Keyphrases

drug induced
liver injury
molecular docking
adverse drug
electronic health record